Article

Rapid, in-patient adaptations of <i>Legionella pneumophila</i> to the human host

2022-05-23

Abstract excerpt

Legionella pneumophila are host-adapted bacteria that infect and reproduce primarily in amoeboid protists. Using similar infection mechanisms, they infect human macrophages, and cause Legionnaires’ disease, an atypical pneumonia, and the milder Pontiac fever. We hypothesized that, despite these similarities, the hosts are different enough so that there exist high-selective value mutations that would dramatically i...

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Literature Corpus work: b0508b77-41b8-59d8-bf9a-d0781fb0c72d
DOI: 10.1101/2022.05.23.492981

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Rapid, in-patient adaptations of <i>Legionella pneumophila</i> to the human hostDOI 10.1101/2022.05.23.492981Read

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