Back to search

Article

Deciphering the spatio-temporal transcriptional and chromatin accessibility of human retinal organoid development at the single cell level

2023-07-19

Abstract excerpt

Molecular information on the early stages of human retinal development remains scarce due to limitations in obtaining early human eye samples. Pluripotent stem cell-derived retinal organoids provide an unprecedented opportunity for studying early retinogenesis. Using a combination of single cell RNA-Seq and spatial transcriptomics we present for the first-time a single cell spatio-temporal transcriptome of retinal...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b045288b-b0fe-5c4f-bba6-660602ca3fdb
DOI
10.1101/2023.07.19.549507
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Deciphering the spatio-temporal transcriptional and chromatin accessibility of human retinal organoid development at the single cell levelDOI 10.1101/2023.07.19.549507
Select a neighboring publication to make it the new centre.