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A single mutation G454A in P450 <i>CYP9K1</i> drives pyrethroid resistance in the major malaria vector <i>Anopheles funestus</i> reducing bed net efficacy

2024-04-23

Abstract excerpt

Metabolic resistance to pyrethroids is jeopardizing the effectiveness of insecticide-based interventions against malaria. The complexity of the Africa-wide spatio-temporal evolution of the molecular basis of this resistance, the major genetic drivers should be detected to improve resistance management. Here, we demonstrated that a single amino acid change G454A in the cytochrome P450 CYP9K1 drives pyrethroid resi...

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Literature Corpus work
b03a56c4-a3c4-58c6-ac30-44ce2d35655b
DOI
10.1101/2024.04.22.590515
Open publication

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A single mutation G454A in P450 <i>CYP9K1</i> drives pyrethroid resistance in the major malaria vector <i>Anopheles funestus</i> reducing bed net efficacyDOI 10.1101/2024.04.22.590515
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