Article
A novel nanoluciferase transgenic reporter to measure proteinuria in zebrafish
2021-07-19
Abstract excerpt
The zebrafish is an important animal system for modelling human diseases. This includes kidney dysfunction as the embryonic kidney (pronephros) shares considerable molecular and morphological homology with the human nephron. Zebrafish also have a high fecundity, with females capable of laying 200-300 eggs per week, thereby facilitating chemical and mutation screening. A key clinical indicator of kidney disease is...
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Identifiers and source
- Literature Corpus work
- b01ce48c-0d73-5e00-a08d-604271f053ed
- DOI
- 10.1101/2021.07.19.452884