Article

Custom Probe-Based Spatial Transcriptomics Enables Microbiome Detection in FFPE Colorectal Cancer Tissue

2026-08-26

Abstract excerpt

<title>Abstract</title> <p> Intratumoral bacteria have emerged as functionally relevant components of the tumor microenvironment, yet the spatial relationship between these bacterial communities and host gene expression remains poorly characterized, in part due to methodological constraints. Existing spatial transcriptomics approaches for microbial detection rely on fresh frozen tissue, excluding FFPE specimens...

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Literature Corpus work: b00117f9-31a3-5837-8286-3fd397436d10
DOI: 10.21203/rs.3.rs-10554418/v1

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