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Misclassification of heritable mortality undermines estimates of intrinsic life span heritability

2026-02-27

Abstract excerpt

In a recent article in Science , Shenhar et al. report that human life span heritability reaches ∼55% after removing “extrinsic” mortality, roughly seven-fold higher than recent large pedigree estimates. This conclusion rests on classifying deaths from infections and accidents as environmental noise independent of genetics. This premise is biologically untenable: susceptibility to severe infection is substantiall...

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Literature Corpus work
afd0f561-24b1-5ace-84d1-b1cbabbf9e6c
DOI
10.64898/2026.02.26.26347172
Open publication

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Misclassification of heritable mortality undermines estimates of intrinsic life span heritabilityDOI 10.64898/2026.02.26.26347172
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