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Omitted familial extrinsic risk inflates inferred intrinsic lifespan heritability

2026-04-06

Abstract excerpt

Shenhar et al. (2026) report 50% “intrinsic” lifespan heritability after calibrating a one-component correlated-frailty survival model to Scandinavian twin lifespans. Their framework is mathematically coherent, but the intrinsic component is not identified if heritable, mortality-relevant extrinsic susceptibility is omitted at calibration. We show that one-component calibration absorbs omitted familial extrinsic s...

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Literature Corpus work
0364652f-dfa3-549f-b75c-7881f86fe075
DOI
10.64898/2026.04.02.716222
Open publication

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Omitted familial extrinsic risk inflates inferred intrinsic lifespan heritabilityDOI 10.64898/2026.04.02.716222
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