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Article

Commonly used estimates of the genetic contribution to disease are subject to the same fallacies as bad luck estimates.

European journal of epidemiology - 1 Nov 2019

Björk Jonas, Andersson Tomas, Ahlbom Anders

Abstract excerpt

The scientific debate following the initial formulation of the "bad luck" hypothesis in cancer development highlighted how measures based on analysis of variance are inappropriately used for risk communication. The notion of "explained" variance is not only used to quantify randomness, but also to quantify genetic and environmental contribution to disease in heritability coefficients. In this paper, we...

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Identifiers

PMID: 31641918
DOI: 10.1007/s10654-019-00573-8
PMCID: PMC6861200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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