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Integrated machine learning survival framework for consensus modeling in a large multicenter cohort of NSCLC resistant to aumolertinib

2025-05-07

Abstract excerpt

<title>Abstract</title> <p>Patients with advanced non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations often benefit from third-generation tyrosine kinase inhibitors (TKIs), such as aumolertinib (AUM). However, the development of drug resistance significantly limits the clinical efficacy of AUM. To address this, we established an in vitro model of AUM-resistant cell lines...

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Literature Corpus work
af7a6148-82e3-5327-a1a6-5cd9438d3210
DOI
10.21203/rs.3.rs-6311145/v1
Open publication

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Integrated machine learning survival framework for consensus modeling in a large multicenter cohort of NSCLC resistant to aumolertinibDOI 10.21203/rs.3.rs-6311145/v1
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