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Bulk RNA analysis identified the characteristics and immunoinvasive patterns of osimertinib resistance in patients with non-small cell lung cancer

2024-09-11

Abstract excerpt

<title>Abstract</title> <p>Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality worldwide, with epidermal growth factor receptor (EGFR) mutations being a common driver. Osimertinib, a third-generation EGFR tyrosine kinase inhibitor (TKI), has shown efficacy in treating NSCLC patients harboring EGFR mutations. However, resistance to osimertinib poses a significant clinical challen...

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Literature Corpus work
6f25ce82-77dd-596e-a15a-24b6fface467
DOI
10.21203/rs.3.rs-4829536/v1
Open publication

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