Article

A new single-cell level R-index for EGFR-TKI resistance and survival prediction in LUAD

2021-08-01

Abstract excerpt

<h4>ABSTRACT</h4> EGFR-TKIs achieved excellent efficacy in EGFR-mutated patients. Unfortunately, most patients would inevitably develop progressive disease within a median of 10 to 14 months. Predicting the resistance probability remains a challenge. Therefore, we created an R-index model trained by single-cell RNA data with the OCLR algorithm. This model can be applied to estimate the level of EGFR-TKI resistanc...

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Literature Corpus work: 272256d1-c39b-58be-80ea-050f5d89e04c
DOI: 10.1101/2021.07.30.454426

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