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Identification of biomarkers, pathways and potential therapeutic targets for EGFR-TKI resistance in non-small-cell lung cancer

2022-05-13

Abstract excerpt

<h4>Background: </h4> Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) have been proven to provide survival benefits for non-small-cell lung cancer (NSCLC), but drug resistance represents a major therapeutic challenge. This study aimed to map the hub genes and potential pathways that might be involved in the molecular pathogenesis of EGFR-TKI resistance in NSCLC. <h4>Methods:</h4> We perform...

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Literature Corpus work
47354ce3-69d9-5d56-8e93-0eca552bef8a
DOI
10.21203/rs.3.rs-1628147/v1
Open publication

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Identification of biomarkers, pathways and potential therapeutic targets for EGFR-TKI resistance in non-small-cell lung cancerDOI 10.21203/rs.3.rs-1628147/v1
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