Article

Shared developmental gait disruptions across two mouse models of neurodevelopmental disorders

2020-10-12

Abstract excerpt

Motor deficits such as abnormal gait are an underappreciated yet characteristic phenotype of many neurodevelopmental disorders (NDDs), including Williams Syndrome (WS) and Neurofibromatosis Type 1 (NF1). Compared to cognitive phenotypes, gait phenotypes are readily and comparably assessed in both humans and model organisms, and are controlled by well-defined CNS circuits. Discovery of a common gait phenotype betwe...

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Literature Corpus work: af725d0b-4e65-5820-9540-758d2908ef62
DOI: 10.1101/2020.10.12.336586

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