Article

Using Histopathology Images to Predict Chromosomal Instability in Breast Cancer: A Deep Learning Approach

2020-09-24

Abstract excerpt

Chromosomal instability (CIN) is a hallmark of human cancer that involves mis-segregation of chromosomes during mitosis, leading to aneuploidy and genomic copy number heterogeneity. CIN is a prognostic marker in a variety of cancers, yet, gold-standard experimental assessment of chromosome mis-segregation is difficult in the routine clinical setting. As a result, CIN status is not readily testable for cancer patie...

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Literature Corpus work: af30670d-531f-5bce-a466-3e899b2174a4
DOI: 10.1101/2020.09.23.20200139

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