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A Common Polymorphism in RNASE6 Impacts Its Antimicrobial Activity Toward Uropathogenic <em>Escherichia coli</em>

2023-11-09

Abstract excerpt

Human Ribonuclease (RNase) 6 is a monocyte and macrophage-derived protein with potent an-timicrobial activity toward uropathogenic bacteria. The RNASE6 gene is heterogeneous in hu-mans due to the presence of single nucleotide polymorphisms (SNPs). RNASE6 rs1045922 is the most common non-synonymous SNP, resulting in a G to A substitution that determines an ar-ginine (R) to glutamine (Q) transversion at position 66...

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Literature Corpus work
af24c322-ca22-5791-b93a-ec036e42f3bf
DOI
10.20944/preprints202311.0606.v1
Open publication

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A Common Polymorphism in RNASE6 Impacts Its Antimicrobial Activity Toward Uropathogenic <em>Escherichia coli</em>DOI 10.20944/preprints202311.0606.v1
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