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New Histone H4 variant and H2B variant Exhibits Distinct Genomic Locations, Chromatin Affinities, and Dynamics Throughout Life Cycle and Cell Cycle of <i>Trypanosoma cruzi</i>

2025-06-20

Abstract excerpt

Histone variants play crucial roles in chromatin organization and transcriptional regulation in eukaryotes. Unusually, trypanosomatids display histone variants for all histones, although a functional homolog of histone H4 variant (H4.V) had not yet been described in Trypanosoma cruzi . In this study, we identified a H4.V in T. cruzi that is encoded by a single-copy gene located apart from the typical tandem arra...

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Literature Corpus work
aeda4d2d-fc01-5e48-bcfb-9fe626aaf516
DOI
10.1101/2025.06.20.660671
Open publication

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New Histone H4 variant and H2B variant Exhibits Distinct Genomic Locations, Chromatin Affinities, and Dynamics Throughout Life Cycle and Cell Cycle of <i>Trypanosoma cruzi</i>DOI 10.1101/2025.06.20.660671
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