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Histone H2B.V demarcates strategic regions in the <i>Trypanosoma cruzi</i> genome, associates with a bromodomain factor and affects parasite differentiation and host cell invasion

2021-06-08

Abstract excerpt

Histone variants play a crucial role in chromatin structure organization and gene expression. Trypanosomatids have an unusual H2B variant (H2B.V) that is known to dimerize with the variant H2A.Z generating unstable nucleosomes. Previously, we found that H2B.V protein is enriched in nonreplicative life forms of Trypanosoma cruzi, suggesting that this variant may contribute to the differences in chromatin structure...

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Literature Corpus work
3b40063e-1597-5902-8b17-e693ffb7d0a4
DOI
10.1101/2021.06.08.447515
Open publication

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Histone H2B.V demarcates strategic regions in the <i>Trypanosoma cruzi</i> genome, associates with a bromodomain factor and affects parasite differentiation and host cell invasionDOI 10.1101/2021.06.08.447515
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