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Genome-Wide DNA Methylation Profiling Reveals Enrichment of Developmental Vascular and Muscle Programs in Peripheral Artery Disease: A Pilot Epigenome-Wide Association Study

2026-08-05

Abstract excerpt

<h4>Background</h4> Peripheral artery disease (PAD) is a common atherosclerotic condition with incompletely understood molecular drivers. DNA methylation is a key epigenetic regulator influenced by smoking, aging, and metabolic risk factors, yet genome-wide methylation patterns specifically associated with PAD remain understudied. <h4>Objective</h4> To characterize genome-wide DNA methylation patterns associated...

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Literature Corpus work: aea05fb4-d26d-51cc-8001-51dfb319b9d8
DOI: 10.64898/2026.08.03.26359321

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