Article

Sulfasalazine promotes myogenic differentiation via increasing of fast myosin heavy chain isoforms

2023-08-16

Abstract excerpt

Sarcopenia is a debilitating condition characterized by the progressive and generalized degeneration of skeletal muscle mass and function. As of now, there is no approved pharmacological treatment for sarcopenia. Previously, our research revealed that Yin Yang 1 (YY1) plays a crucial role in PHD finger protein 20 (PHF20)-mediated myogenic differentiation. A significant enhancement in YY1 transcription, mediated by...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ae9ed4f7-9f0a-51db-accf-1a5d8b75c6fe
DOI: 10.1101/2023.08.15.553466

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sulfasalazine promotes myogenic differentiation via increasing of fast myosin heavy chain isoformsDOI 10.1101/2023.08.15.553466Read

Oligonucleotide Therapeutics for Age-Related Musculoskeletal Disorders: Successes and ChallengesSemantic proximity Read

Identification of a KLF5-dependent program and drug development for skeletal muscle atrophySemantic proximity Read

Enhancement of Prednisolone efficacy and safety in Duchenne muscular dystrophy via neutrophil elastase inhibitionSemantic proximity Read

Exercise-Induced Myostimulin Enhances Muscle Function in Health and DiseaseSemantic proximity Read

The JAK/STAT Pathway in Skeletal Muscle PathophysiologySemantic proximity Read

Y Chromosome Genes May Play Roles in Directed Differentiation of Human Embryonic Stem Cells.Semantic proximity Read

Epigenetic small molecule screening identifies a new HDACi compound for ameliorating Duchenne muscular dystrophySemantic proximity Read

Targeted Screening and Identification of Chlorhexidine as a Pro-myogenic Circadian Clock ActivatorSemantic proximity Read

Modulating Myogenesis: An Optimized In Vitro Assay to Pharmacologically Influence Primary Myoblast DifferentiationSemantic proximity Read

Molecular mechanism of sphingosine-1-phosphate action in Duchenne muscular dystrophy.Semantic proximity Read

IMB0901 inhibits muscle atrophy induced by cancer cachexia through MSTN signaling pathwaySemantic proximity Read

Daidzein Inhibits Muscle Atrophy by Suppressing Inflammatory Cytokine- and Muscle Atrophy-Related Gene ExpressionSemantic proximity Read