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Article

Short-term Topiramate treatment prevents radiation-induced cytotoxic edema in preclinical models of breast-cancer brain metastasis

2023-02-15

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Brain edema is a common complication of brain metastases (BM) and associated treatment. The extent to which cytotoxic edema, the first step in the sequence that leads to ionic edema, vasogenic edema and brain swelling, contributes to radiation-induced brain edema during BM remains unknown. This study aimed to determine whether radiation-associated treatment of BM induces cyt...

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Literature Corpus work
ae7bcfef-19fe-5b45-bf5c-d048531af6ab
DOI
10.1101/2023.02.14.528559
Open publication

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Short-term Topiramate treatment prevents radiation-induced cytotoxic edema in preclinical models of breast-cancer brain metastasisDOI 10.1101/2023.02.14.528559
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