Article

Valproic Acid as Adjuvant Treatment for Convulsive Status Epilepticus: a Randomised Clinical Trial

2022-09-20

Abstract excerpt

<h4>Background: </h4> Generalised convulsive status epilepticus (GCSE) is a medical emergency. Guidelines recommend a stepwise strategy of benzodiazepines followed by a second-line anti-seizure medicine (ASM). However, GCSE is uncontrolled in 20–40% patients and is associated with protracted hospitalisation, disability, and mortality. The objective was to determine whether valproic acid (VPA) as complementary trea...

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Literature Corpus work: ae3e3340-6c1b-5204-babf-d23a6570e24c
DOI: 10.21203/rs.3.rs-2070140/v1

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