Article

Phenobarbital as an Adjuvant to benzodiazepine administration when compared to Single-agent benzodiazepine Treatment (usual care) for Alcohol Withdrawal Syndrome in the Intensive Care Unit (PASTA): a study protocol for a feasibility trial that embeds screening, enrolment and randomization within the electronic medical records

2025-10-15

Abstract excerpt

<title>Abstract</title> <p>Background Abrupt cessation of alcohol consumption following hospital admission can induce alcohol withdrawal syndrome. This syndrome is challenging to manage and is associated with considerable morbidity and mortality. Current management of alcohol withdrawal syndrome in Australia is generally titrated benzodiazepine administration. In some regions, phenobarbital is preferred but evide...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0f40e0e0-2f90-5f6f-b2b0-e2aea6ec04dc
DOI: 10.21203/rs.3.rs-7521474/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Phenobarbital as an Adjuvant to benzodiazepine administration when compared to Single-agent benzodiazepine Treatment (usual care) for Alcohol Withdrawal Syndrome in the Intensive Care Unit (PASTA): a study protocol for a feasibility trial that embeds screening, enrolment and randomization within the electronic medical recordsDOI 10.21203/rs.3.rs-7521474/v1Read

Prospective pragmatic quasi-experimental study to assess the impact and effectiveness of alcohol care teams (ACTs) targeting adults with alcohol dependence admitted to NHS Hospitals in England: the ProACTIVE † prospective patient study protocolSemantic proximity Read

Review article: pharmacotherapy for alcohol dependence - the why, the what and the wherefore.Semantic proximity Read

Comparison of Intramuscular Pharmacological Treatment Options for Acute Agitation: A Multicenter Retrospective Cohort StudySemantic proximity Read

Deprescribing To Reduce Polypharmacy: Study Protocol For A Randomised Controlled Trial Assessing Deprescribing of Anticholinergic and Sedative Drugs In A Cohort of Frail Older People Living In The CommunitySemantic proximity Read

Pharmacotherapy for alcohol dependence: A stratified approach.Semantic proximity Read

The efficacy of iCBT added to treatment as usual for alcohol dependent patients in Primary Care: study protocol for a randomized controlled trial.Semantic proximity Read

Current Pharmacotherapies for Alcohol Use Disorder in Italy: From Neurobiological Targets to Clinical PracticeSemantic proximity Read

Pharmacological class interventions for benzodiazepine withdrawal discontinuation: a meta-analysisSemantic proximity Read

Effectiveness of screening and ultra-brief alcohol intervention in primary care: a pragmatic cluster randomised controlled trialSemantic proximity Read

Large-scale automated phenotyping of cardiac arrest and withdrawal of life-sustaining therapy using electronic health record data.Semantic proximity Read

Benzodiazepine Withdrawal Symptom Clusters: Distinct Phenotypes with Treatment ImplicationsSemantic proximity Read

Naltrexone vs Placebo for the Treatment of Alcohol Dependence: A Randomized Clinical Trial.Semantic proximity Read