Article

Population-specific Risk of Pharmacogenomics-related Inaccurate Drug Dosing of ICU Patients

2025-02-14

Abstract excerpt

<h4>Rationale</h4> Intensive care units (ICU) patients are highly vulnerable to inaccurate drug dosing. Pharmacogenomics (PGx) characterizes the influence of inherited genetic variation on drug metabolism, playing an important role in the consequences of a given drug dose. <h4>Objectives</h4> To assess the genetic-based risk of inaccurate drug dosing in the ICU. <h4>Methods</h4> We carried out whole genome sequenc...

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Literature Corpus work: ae3cef90-e5c3-5557-a2f5-4145d2a5443d
DOI: 10.1101/2025.02.11.25321889

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