Article

Critically Ill Children Frequently Receive Medications with Established but Unused Pharmacogenomic Guidelines: Actionable Findings from an Integrated Electronic Medical Record and Exome Sequencing Study

2026-07-20

Abstract excerpt

<h4>Importance</h4> Pharmacogenomic (PGx) guidelines can improve medication efficacy and reduce toxicity, but their application in pediatric intensive care units (PICUs) remains largely unexplored. <h4>Objective</h4> To determine the frequency of medications with established PGx guidelines administered in the PICU and assess the capacity of exome sequencing to capture PGx phenotypes for these medications. <h4>De...

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Literature Corpus work: 7214dec2-86aa-5e50-8418-b6c8473dce82
DOI: 10.64898/2026.07.16.26358240

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