Article
Success and failure of triptans
2001-06-01
Abstract excerpt
Sumatriptan and the newer triptans (zolmitriptan, naratriptan, rizatriptan, eletriptan, almotriptan, frovatriptan and donitriptan) display high agonist activity at 5-HT1B and 5-HT1D receptors. Most triptans, but not all (donitriptan, frovatriptan and rizatriptan), also have a high affinity at the 5-ht1F receptor. In anaesthesisted animals, triptans decrease the arteriovenous anastomotic fraction of carotid blood f...
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Identifiers and source
- Literature Corpus work
- ae3ad6c6-7bdd-590d-92c5-1ab3643a6601
- DOI
- 10.1007/s101940170040
- PMCID
- PMC3611827