Article

Association between resting-state functional brain connectivity and gene expression is altered in autism spectrum disorder

2021-01-08

Abstract excerpt

Gene expression covaries with brain activity as measured by resting state functional MRI. However, it is unclear how genomic differences driven by disease state can affect this relationship. Here, we integrate brain gene expression datasets of neurotypical controls and autistic (ASD) patients with regionally matched brain activity measurements from fMRI datasets. We identify genes linked with brain activity whose...

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Literature Corpus work: ae386a0a-f36a-51d6-87ea-bf518c4f61d5
DOI: 10.1101/2021.01.07.21249281

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