Article

Distinct transcriptomic and hierarchical organization associated with brain hyperconnectivity and hypoconnectivity in autism spectrum disorder

2026-08-01

Abstract excerpt

Functional hyperconnectivity and hypoconnectivity in autism spectrum disorder (ASD) are typically treated as opposing expressions of a single circuit-level disturbance, but their molecular and hierarchical basis remains unclear. We combined resting-state fMRI from 1,737 individuals from the Autism Brain Imaging Data Exchange (ABIDE I/II) with gene-expression maps from the Allen Human Brain Atlas and show that hype...

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Literature Corpus work: a4036d1d-bf7e-592f-8d86-138f768dabed
DOI: 10.64898/2026.07.31.742105

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