Article
Autism susceptibility genes and the transcriptional landscape of the human brain.
International review of neurobiology - 1 Jan 2013
Miyauchi Shingo, Voineagu Irina
Abstract excerpt
Autism is the most severe end of a spectrum of neurodevelopmental conditions, autism spectrum disorders (ASD). ASD are genetically heterogeneous, and hundreds of genes have been implicated in the etiology of the disease. Here, we discuss the contribution of brain transcriptome studies in advancing our understanding of the genetic mechanisms of ASD and review recent work characterizing the spatial and temporal...
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