Article

Finerenone attenuates myocardial apoptosis, metabolic disturbance and myocardial fibrosis in type 2 diabetes mellitus

2022-12-20

Abstract excerpt

<h4>Background: </h4> Finerenone is a third-generation mineralocorticoid receptor antagonists, which has shown good cardiac function improvement in patients with type 2 diabetes in large-scale clinical trials. However, its specific role in diabetic cardiomyopathy remains unclear. We explored the potential functions and mechanisms of finerenone in diabetic cardiomyopathy. Methods After Sprague‐Dawley rats were indu...

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Literature Corpus work: ae32d1c4-2a29-5a36-9b14-20930a4263ab
DOI: 10.21203/rs.3.rs-2372964/v1

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