Article

Novel Oral-edaravone Attenuates Diastolic Dysfunction of Diabetic Cardiomyopathy via Activating the Nrf2 Signaling Pathway

2021-09-28

Abstract excerpt

<title>Abstract</title> <p>Background Diastolic dysfunction is the most common change of diabetic cardiomyopathy (DCM), but there is no effective clinical treatment at present. Oxidative stress plays a crucial role in the pathophysiological process of diabetic diastolic dysfunction including hypertrophy, apoptosis and fibrosis. The novel Oral-edaravone (OED) alleviates oxidative stress by scavenging free radical...

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Literature Corpus work: 5e118d70-9e89-5306-b3ec-b8ac9301e199
DOI: 10.21203/rs.3.rs-936670/v1

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