Article
Differential effects of follicle-stimulating hormone glycoforms on the transcriptome profile of cultured rat granulosa cells as disclosed by RNA-seq
2023-10-21
Abstract excerpt
<h4>ABSTRACT</h4> It has been documented that variations in glycosylation on glycoprotein hormones, confer distinctly different biological features to the corresponding glycoforms when multiple in vitro biochemical readings are analyzed. We here applied next generation RNA sequencing to explore changes in the transcriptome of rat granulosa cells exposed for 0, 6, and 12 h to 100 ng/ml of four highly purified fol...
Topics
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- Estrogen and related hormone effects
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genetic and phenotypic traits in livestock
- Glycosylation and Glycoproteins Research
- Growth Hormone and Insulin-like Growth Factors
- Hypothalamic control of reproductive hormones
- Ovarian function and disorders
- Reproductive Biology and Fertility
Identifiers and source
- Literature Corpus work
- ae16da44-cdff-5207-b1e4-728643421b0d
- DOI
- 10.1101/2023.10.18.562995
