Article

Shared genetic risk factors and their implications for treatment of IPF and systemic hypertension

2023-06-05

Abstract excerpt

More than 50% of individuals with idiopathic pulmonary fibrosis (IPF) have co-morbid hypertension. High blood pressure can lead to organ fibrosis or can be a consequence of artery stiffening due to fibrosis. Studies have implicated common processes, such as TGF-β signalling, in both traits’ regulation. Our goal is to identify shared genetic risk factors for IPF and hypertension. We analysed the genome-wide genetic...

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Literature Corpus work: ae0ffcd1-90ed-529b-bb98-4866fb639da7
DOI: 10.1101/2023.06.02.23290865

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