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Meta-analysis defines predominant shared microbial responses in various diseases and a specific inflammatory bowel disease signal

23 Feb 2022

Abstract excerpt

BACKGROUND: Gut microbial alteration is implicated in inflammatory bowel disease but is noted in other diseases. Systematic comparison to define similarities and specificities is hampered since most studies focus on a single disease. RESULTS: We develop a pipeline to compare between disease cohorts starting from the raw V4 16S amplicon sequence variants. Including 12,838 subjects, from 59 disease cohorts, we...

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PMID: 35197084
DOI: 10.1186/s13059-022-02637-7

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