Article

A deep unsupervised language model for protein design

2022-03-12

Abstract excerpt

Protein design aims to build new proteins from scratch thereby holding the potential to tackle many environmental and biomedical problems. Recent progress in the field of natural language processing (NLP) has enabled the implementation of ever-growing language models capable of understanding and generating text with human-like capabilities. Given the many similarities between human languages and protein sequences,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ad9e9c19-aa7b-5a2d-a31b-00810e80e82d
DOI: 10.1101/2022.03.09.483666

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A deep unsupervised language model for protein designDOI 10.1101/2022.03.09.483666Read

Pretrained protein language models choose between sequence novelty and structural completenessSemantic proximity Read

Protein Design with StructureGPT: a Deep Learning Model for Protein Structure-to-Sequence TranslationSemantic proximity Read

Mixture of Experts Enable Efficient and Effective Protein Understanding and DesignSemantic proximity Read

InstructPLM: Aligning Protein Language Models to Follow Protein Structure InstructionsSemantic proximity Read

BIOFORMERS: A SCALABLE FRAMEWORK FOR EXPLORING BIOSTATES USING TRANSFORMERSSemantic proximity Read

InstructPLM: Aligning Protein Language Models to Follow Protein Structure InstructionsSemantic proximity Read

Protein design and variant prediction using autoregressive generative models.Semantic proximity Read

Applying Protein Language Models Using Limited Dataset. Sequence-Based Hot Spot Prediction in Protein Interactions Using AutoGluonSemantic proximity Read

Adapting protein language models for structure-conditioned designSemantic proximity Read

LM-PROTAC: a language model-driven PROTAC generation pipeline with dual constraints of structure and propertySemantic proximity Read

yakRNA Design: A semantic multimodal RNA composerSemantic proximity Read

ProtWave-VAE: Integrating Autoregressive Sampling with Latent-Based Inference for Data-Driven Protein Design.Semantic proximity Read