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Article

Mining kidney toxicogenomic data by using gene co-expression modules.

BMC genomics - 10 Oct 2016

AbdulHameed Mohamed Diwan M, Ippolito Danielle L, Stallings Jonathan D, Wallqvist Anders

Abstract excerpt

BACKGROUND: Acute kidney injury (AKI) caused by drug and toxicant ingestion is a serious clinical condition associated with high mortality rates. We currently lack detailed knowledge of the underlying molecular mechanisms and biological networks associated with AKI. In this study, we carried out gene co-expression analyses using DrugMatrix-a large toxicogenomics database with gene expression data from rats...

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Identifiers

PMID: 27724849
DOI: 10.1186/s12864-016-3143-y
PMCID: PMC5057266

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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