Article

Integrative Spatial Modelling of Cellular Plasticity using Graph Neural Networks and Geostatistics

2025-09-25

Abstract excerpt

Cellular plasticity - the ability of cells to change phenotype in response to intrinsic and environmental cues - is central to development, regeneration, and disease, but remains difficult to quantify due to its dynamic, context-dependent nature. Here we introduce a framework that unites AI and geostatistics - graph neural networks and spatial regression models - to both predict and explain cell state variation in...

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Literature Corpus work: ad5a3e26-5943-5006-92f4-f037c02f4279
DOI: 10.1101/2025.09.24.678189

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