Article

Decoding the IGF1 Signaling Gene Regulatory Network Behind Alveologenesis from A Mouse Model of Bronchopulmonary Dysplasia

2022-01-25

Abstract excerpt

<h4>Summary</h4> Lung development is precisely controlled by underlying Gene Regulatory Networks (GRN). Disruption of genes in the network can interrupt normal development and cause diseases such as bronchopulmonary dysplasia (BPD)–a chronic lung disease in preterm infants with morbid and sometimes lethal consequences characterized by lung immaturity and reduced alveolarization. Here, we generated a transgenic mo...

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Literature Corpus work: 6b04dd4d-0fd8-59a8-91cf-3ab4fda76c7b
DOI: 10.1101/2022.01.24.477613

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