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Article

The role of the atypical chemokine receptor CCRL2 in myelodysplastic syndrome and secondary acute myeloid leukemia

2021-07-30

Abstract excerpt

<h4>ABSTRACT</h4> The identification of new molecular pathways supporting the growth of myelodysplastic syndrome (MDS) stem and progenitor cells is needed to understand clinical variation and develop targeted therapies. Within myeloid malignancies, men have worse outcomes compared to women, suggesting male sex hormone driven effects in malignant hematopoiesis. The androgen receptor promotes the expression of five...

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Literature Corpus work
ad35c752-6d99-565c-8a3e-4188fc09b0c0
DOI
10.1101/2021.07.29.454394
Open publication

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