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Evaluation of tumour perfusion and fibrosis in mouse models of pancreatic ductal adenocarcinoma, using MRI

2013-01-01

Abstract excerpt

Pancreatic Ductal Adenocarcinoma (PDA) is one of the most lethal solid malignancies primarily because it is staunchly resistant to conventional cytotoxic chemotherapies. Xenograft models are typically not sophisticated enough to reproduce the complex pathophysiology of the clinical disease. This is the main reason why treatments that have shown promise in preclinical mouse models have not translated into improveme...

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Literature Corpus work
ad0ceed1-3210-5461-b0e0-0718a9e81f56
DOI
10.17863/cam.11793
Open publication

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