Article

Single-cell and spatial multiomic inference of gene regulatory networks using SCRIPro

2023-12-23

Abstract excerpt

The accurate reconstruction of gene regulation networks (GRNs) from sparse and noisy single-cell or spatial multi-omics data remains a challenge. Here, we present SCRIPro, a comprehensive computational framework that robustly infers GRNs for both single-cell and spatial multi-omics data. SCRIPro first addresses sample sparseness by a density clustering approach. SCRIPro assesses transcriptional regulator (TR) impo...

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Literature Corpus work: acb7fbe0-5a59-53d0-a4fa-bbcc25d4db1e
DOI: 10.1101/2023.12.21.572934

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