Article

Ipsilateral or contralateral boosting of mice with mRNA vaccines confers equivalent immunity and protection against a SARS-CoV-2 Omicron strain

2024-04-07

Abstract excerpt

<h4>ABSTRACT</h4> Boosting with mRNA vaccines encoding variant-matched spike proteins has been implemented to mitigate their reduced efficacy against emerging SARS-CoV-2 variants. Nonetheless, in humans, it remains unclear whether boosting in the ipsilateral or contralateral arm with respect to the priming doses impacts immunity and protection. Here, we boosted K18-hACE2 mice with either monovalent mRNA-1273 (Wuh...

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Literature Corpus work: acafee37-08f0-507f-959b-d06cf60558f6
DOI: 10.1101/2024.04.05.588051

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