Article

Ex vivo effects of low dose delayed release rapamycin on agonist-induced platelet aggregation, activation and procoagulant platelet phenotypes in domestic cats

2025-11-11

Abstract excerpt

<title>Abstract</title> <p> Cardiogenic arterial thromboembolism (CATE) is a complication of hypertrophic cardiomyopathy (HCM) with a high mortality rate. Despite anti-platelet drugs use, on-treatment recurrence rate remains high indicating a critical need to discover novel therapies. Studies in both humans and cats show that low dose delayed release rapamycin (LDDRR) can reduce the progression of left ventricul...

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Literature Corpus work: acadb172-0168-5c85-a5d2-8f9a9ed4b78f
DOI: 10.21203/rs.3.rs-7068900/v1

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