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A novel Erg3 T208I substitution mediates triazole resistance in Talaromyces marneffei clinical isolates from HIV/AIDS patients in southern China

2026-04-22

Abstract excerpt

<title>Abstract</title> <p> <italic>Talaromyces marneffei</italic> ( <italic>T. marneffei</italic> ) is a life-threatening dimorphic fungus endemic to southern China and Southeast Asia, with triazole resistance emerging as a critical clinical challenge in immunocompromised populations, particularly HIV/AIDS patients. This study aimed to characterize the molecular mechanisms underlying triazole resistance in c...

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Literature Corpus work
ac8fe1d0-883c-5f84-8dd0-bdc5e2a13cae
DOI
10.21203/rs.3.rs-9153081/v1
Open publication

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A novel Erg3 T208I substitution mediates triazole resistance in Talaromyces marneffei clinical isolates from HIV/AIDS patients in southern ChinaDOI 10.21203/rs.3.rs-9153081/v1
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