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Phenotypic and Molecular Characterization of Three Clinical Voriconazole- Resistant Aspergillus fumigatus Isolates Harboring TR46/M143L Mutations in cyp51A

2026-06-12

Abstract excerpt

<title>Abstract</title> Azole-resistant <italic>Aspergillus fumigatus</italic> poses an increasing clinical challenge. In this study, 22 clinical <italic>A. fumigatus</italic> isolates from southwestern China were identified by morphological and molecular approaches, and their azole susceptibility was determined using broth microdilution and disk diffusion assays. Three isolates exhibiting high-level vor...

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Literature Corpus work: 539c1c1c-c255-5491-8abf-3a487c6794a6
DOI: 10.21203/rs.3.rs-9753663/v1

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