Article

Optimization of Expression, Purification and Secretion of Functional Recombinant Human Growth Hormone in Prokaryotic Hosts Using Modified Staphylococcal Protein A Signal Peptide

2021-03-11

Abstract excerpt

<h4>Background: </h4> Human Growth Hormone (hGH) is a glycoprotein released from the pituitary gland. Due to the wide range of effects in humans, any disruption in hGH secretion could have serious consequences. This highlights the clinical importance of hGH production in the treatment of different diseases associated with a deficiency of this hormone. The production of recombinant mature hormone in suitable hosts...

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Literature Corpus work: ac5238ae-fc96-5222-8c1f-435dd27df3d0
DOI: 10.21203/rs.3.rs-257852/v1

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