Article

<i>CanDrivR-CS</i> : A Cancer-Specific Machine Learning Framework for Distinguishing Recurrent and Rare Variants

2024-09-23

Abstract excerpt

<h4>Motivation</h4> Missense variants play a crucial role in cancer development, and distinguishing between those that frequently occur in cancer genomes and those that are rare may provide valuable insights into important functional mechanisms and consequences. Specifically, if common variants confer growth advantages, they may have undergone positive selection across different patients due to similar selection...

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Literature Corpus work: ac47c995-7974-5ba2-8a8b-83c0d216fddd
DOI: 10.1101/2024.09.19.613896

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