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Elovanoids are neural resiliency epigenomic regulators targeting histone modifications, DNA methylation, tau phosphorylation, telomere integrity, senescence programming, and dendrite integrity

2023-07-21

Abstract excerpt

<title>Abstract</title> <p>Cellular identity, developmental reorganization, genomic structure modulation, and susceptibility to diseases are determined by epigenomic regulation by multiple signaling interplay. Here we demonstrate that elovanoids (ELVs), mediators derived from very-long-chain polyunsaturated fatty acids (VLC-PUFAs, n-3, C > 28), and their precursors in neurons in culture overcome the damage trigge...

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Literature Corpus work
ac3d0c76-d082-558f-91af-0163fdedfd4c
DOI
10.21203/rs.3.rs-3185942/v1
Open publication

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Elovanoids are neural resiliency epigenomic regulators targeting histone modifications, DNA methylation, tau phosphorylation, telomere integrity, senescence programming, and dendrite integrityDOI 10.21203/rs.3.rs-3185942/v1
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