Article

Necdin Inhibits the Proliferation of Osteosarcoma Cells and Lung Metastasis by Wnt/β-catenin signaling pathway

2022-09-02

Abstract excerpt

The emergence of neoadjuvant chemotherapy has improved the prognosis of patients with osteosarcoma (OS), but metastasis and recurrence have become the difficulty of treatment. Necdin (NDN) exists as a tumor suppressor gene in some tumors, but its role in osteosarcoma is not clear, while c-Myc is a clear oncogene. This study found that the expression of NDN is low expressed and c-Myc is high expressed in osteosarco...

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Literature Corpus work: abccdcc5-06b2-5bac-8536-1c8b4d5cbd81
DOI: 10.21203/rs.3.rs-1936030/v1

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