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Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma

25 Mar 2009

Abstract excerpt

Osteosarcoma is the most prevalent bone malignant tumor in children and adolescents, and displays heterogeneous histology and high propensity for distant metastasis. Although adjuvant chemotherapy remarkably improved treatment outcome over the past few decades, prognosis for osteosarcoma patients with pulmonary metastasis is still unsatisfactory. To identify novel therapeutic targets for osteosarcoma, we...

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PMID: 19486338
DOI: 10.1111/j.1349-7006.2009.01165.x

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