Article
Diagnostic potential of vitreoretinal lymphoma by detection of gene mutations with NGS in 25 Chinese patients.
Clinica chimica acta; international journal of clinical chemistry - 15 Jul 2024
Chen Kun, Qin Huanhuan, Li Xiangyu, Zhou Xian, Ma Jingjing, Guan Ming
Abstract excerpt
BACKGROUND: Vitreoretinal lymphoma (VRL) is a rare malignant lymphoproliferative tumor. Our study aimed to investigate the mutational profile of VRL distinguishing from uveitis using next-generation sequencing (NGS) analysis on small amounts of vitreous fluid. METHODS: Vitreous samples from twenty-six eyes of twenty VRL patients and six eyes of five uveitis patients were enrolled. All vitreous samples underwent...
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